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It includes AMR1 (ascorbic acid mannose pathway regulator 1), which transcriptionally represses GDP-l-galactose phosphorylase (GGP) VTC2 (Zhang et al., 2009)

In higher plants, NO is probably generated through a variety of mechanisms, including NO synthase-like activities, polyamine biosynthetic pathways and mitochondrial or peroxisomal pathways 20,23

This result suggests that chronic ALA treatment had little effect on microglia with 4 months of treatment, but possibly increased microglial activation with 11 months of treatment